AANP Adult Gerontology Primary Care Nurse Practitioner Exam 2025 – 400 Free Practice Questions to Pass the Exam

Patients on thiazide diuretics should be closely monitored for hypokalemia because these medications can lead to increased potassium excretion in the urine. Thiazide diuretics work by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, which also affects potassium retention. As sodium is excreted, it pulls potassium out, potentially resulting in lower levels of potassium in the bloodstream. This electrolyte imbalance can lead to symptoms such as muscle weakness, fatigue, and arrhythmias, making it essential for healthcare providers to regularly check potassium levels and educate patients about the signs of hypokalemia.

Monitoring for hyperglycemia, increased calcium excretion, and the use of anticoagulants can also be important in specific contexts or patient populations but is not the primary focus associated with thiazide diuretics. While thiazides can affect glucose metabolism and lead to increased calcium levels in some patients, the risk of hypokalemia is more direct and common with their use.